Gender Impact on Success of Chronic Total Occlusion Percutaneous Coronary Intervention: A Meta-analysis
Background
Prior studies have described significant differences in plaque composition for females compared to males. Impact of this sex-specific differential plaque composition on success of Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI) have not been well studied
Methods
PubMed, EMBASE and Google Scholar databases were queried for all trials about CTO PCI. Trials reporting sex-based outcomes were included
Results
This meta-analysis of 8 CTO trials included 8295 patients, of whom 1477 (18%) were females. Female patients, compared to males, had higher odds for successful CTO PCI (84% vs 80% respectively; OR 0.82, 95% CI 0.70- 0.96)
Conclusions
In this meta-analysis, female patients, compared to males, had higher odds for successful CTO PCI. This analysis supports CTO PCI for symptomatic females