Gender Impact on Success of Chronic Total Occlusion Percutaneous Coronary Intervention: A Meta-analysis

Wednesday, May 22, 2019
Belmont Ballroom 2-3 (The Cosmopolitan of Las Vegas)
Bhavi Pandya , Staten Island University Hospital , Staten Island, NY
David Biglari , Phoenix Veterans Affairs Health Care System, Phoenix, AZ
Nickalaus Gramze , Banner University Medical Center Phoenix, Phoenix, AZ
Todd Hurst , Banner University Medical Center Phoenix, Phoenix, AZ
Ligita Centorino , Banner University Medical Center Phoenix, Phoenix, AZ
Radha Gopalan , Banner University Medical Center Phoenix, Phoenix, AZ
Franciso Arabia , Banner University Medical Center Phoenix, Phoenix, AZ
Kenith Fang , Banner University Medical Center Phoenix, Phoenix, AZ
Wilber Su , Banner University Medical Center Phoenix, Phoenix, AZ
Anantharam Kalya , Banner University Medical Center Phoenix, Phoenix, AZ
Firas Abbas , Banner University Medical Center Phoenix, Phoenix, AZ
Nachiket Patel , Banner University Medical Center Phoenix, Phoenix, AZ
Georeg Gellert , Banner University Medical Center Phoenix, Phoenix, AZ
Samuel M. Butman, M.D., FSCAI , HEART & VASCULAR CENTER OF NORTHERN ARIZONA, Cottonwood, AZ
Frank Tamburrino , Staten Island University Hospital, Staten Island, NY
Ruben Kandov , Staten Island University Hospital, Staten Island, NY
James Lafferty , Staten Island University Hospital, Staten Island, NY
Martha Gulati , Banner University Medical Center Phoenix, Phoenix, AZ
Divya Ratan Verma, M.D. , Banner University Medical Center Phoenix, Phoenix, AZ

Background
Prior studies have described significant differences in plaque composition for females compared to males. Impact of this sex-specific differential plaque composition on success of Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI) have not been well studied

Methods
PubMed, EMBASE and Google Scholar databases were queried for all trials about CTO PCI. Trials reporting sex-based outcomes were included

Results
This meta-analysis of 8 CTO trials included 8295 patients, of whom 1477 (18%) were females. Female patients, compared to males, had higher odds for successful CTO PCI (84% vs 80% respectively; OR 0.82, 95% CI 0.70- 0.96)

Conclusions
In this meta-analysis, female patients, compared to males, had higher odds for successful CTO PCI. This analysis supports CTO PCI for symptomatic females