LB-1
Real-world evaluation of the feasibility and quality of PCI guidance using Dynamic Coronary Roadmap: A secondary analysis of the DCR4Contrast Multicenter, International Randomized Control Trial.
Presenter
John C. Messenger, M.D., FSCAI, University of Colorado Anschutz Medical Campus, Denver, CO
John C. Messenger, M.D., FSCAI1, Aaron Louis Strobel, M.D., FSCAI2, Haim Danenberg, MD3, Frederic De Vroey, MD4, Ajay J. Kirtane, M.D., FSCAI5, Manish A. Parikh, M.D., FSCAI6, Dimitrios Karmpaliotis, M.D., FSCAI7, Breda Hennessey, MD8, Alejandro Curcio, MD9, Martijn van Mourik, MSc, PhD10, Peter Eshuis, MSc, PhD10 and Javier Escaned, M.D., Ph.D.11, (1)University of Colorado Anschutz Medical Campus, Denver, CO, (2)Arkansas Cardiology, Little Rock, AR, (3)Hadassah University Medical Center, Hadassah, Israel, Israel, (4)Grand Hopital de Charleroi, Charleroi, Charleroi, Belgium, (5)NewYork-Presbyterian Columbia University Irving Medical Center, New York, NY, (6)New York-Presbyterian, New York, NY, (7)Atlantic Health Morristown Medical Center, Morristown , NJ, (8)Hospital Clinico San Carlos, Madrid, Madrid, Spain, (9)Hospital Universitario de Fuenlabrada, Madrid, Fuenlabrada, Spain, (10)Philips Healthcare, Cambridge, MA, (11)Hospital Clínico San Carlos, Madrid, Spain
Keywords: Coronary, Imaging & Physiology and Stable Ischemic Heart Disease (SIHD)
Background:
Dynamic Coronary Roadmap is a PCI navigation support tool which may potentially facilitate PCI and increase procedural safety by projecting a virtual coronary roadmap on the moving fluoroscopy, thus potentially decreasing the amount of contrast needed for PCI. While this has been FDA approved, evaluation of the quality of the roadmap for guiding simple and complex PCI has not been compared to standard PCI techniques in a real-world setting.
Methods:
The Dynamic Coronary Roadmap for Contrast Reduction trial (DCR4Contrast) is a multi-center, prospective, unblinded, stratified 1:1 randomized controlled trial investigating the use of Dynamic Coronary Roadmap, an automatic software tool integrated into the interventional X-ray system that provides the PCI operator with a real time, motion compensated dynamic overlay of the coronary tree on fluoroscopy. DCR4Contrast enrolled 371 patients undergoing PCI from six centers in the US and Europe. We will report the endpoint of roadmap quality as evaluated by the operators as well as the quality when used for single versus multivessel PCI.
Results:
This is a placeholder as the enrollment was completed on 2023 Feb 09. Trial results will be available for presentation at SCAI 2023 for the Late Breaking Science session.
Conclusions:
Dynamic Coronary Roadmap has the potential to contribute to increased procedural safety by potentially reducing iodinated contrast utilization and radiation. Key to this is the quality of the roadmaps generated in the real-world setting. This is the first multi-center randomized assessment of the use of this medical device software developed to aid in the performance of PCI.