2021 Scientific Sessions

O-3
PDA occlusion in very low birth weight (VLBW) infants: Comparing the Microvascular Plug and the Piccolo occluder

Presenter

Frank F. Ing, M.D., MSCAI, UC Davis Medical Center, Carmichael, CA
Nithya Sivakumar, MD, UC Davis Medical Center, Sacramento, CA, Andrew Pelech, M.D., FSCAI, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL and Frank F. Ing, M.D., MSCAI, UC Davis Medical Center, Carmichael, CA

Keywords: Congenital Heart Disease (CHD) and Patent Ductus Arteriosus (PDA)

Background


Transcatheter PDA closure (TCPC) in VLBW infants using the Piccolo (P) device & the Microvascular Plug (MVP) has been reported.

Methods
VLBW (1600 ≤ gm) infants who underwent TCPC at our center from 5/18 to 12/20 were included. Pt profile, PDA anatomy, cath lab data & early outcomes using the MVP (group 1) & the Piccolo occlude (group 2) were compared.

Results


45 VLBW infants underwent TCPC during the study period (MVP-19, P -26). Pt profile, PDA anatomy & cath lab data is shown in table 1. Comparing the 2 groups, median gestational age, birth wt, procedure wt & age, PDA anatomy procedure & fluoroscopy time, DAP & contrast used were comparable. In both groups, the vast majority of PDA morphology were type C/F & device diameters used ranged 3-5mm. Device repositioning was needed in 9/19 (47%) in group 1 & 12/26 (46%) in group 2. Successful implant was achieved in 19/19 (100%) in group 1 & 24/26 (92%) in group 2. There were no major complications in both groups. Embolizations (2) occurred in group 2 and were retrieved. Other minor complications were similar for both groups (MVP-4, P-5) and included mild LPA flow acceleration (3) for both groups, mild aortic obstruction (1) in group 1 & mild-moderate tricuspid regurgitation (TR) (2) in group 2.

Conclusions


The MVP & Piccolo devices can be implanted in PDAs of VLBW infants with equal effectiveness. Repositioning of both devices are commonly required. In spite of greater radiolucency of the MVP & the extra catheter exchange for the Piccolo, procedural & flouroscopy time, DAP & contrast used were similar. No major complications were encountered. Minor complications were common for both devices, especially minor LPA obstruction & TR.